Details of a cryofixed Ptk tissue culture cell showing Golgi apparatus, mitochondria and a segment of nucleus with nucleolus at right. 40 nm epon section prepared from plunge frozen,and freeze substit...

Individual Mouse Aortic Endothelial Cell (MAEC) migrating in a 3-dimensional collagen gel (1.4mg/mL). Imaged on a spinning disk confocal microscope using a 100x oil immersion objective lens on a Nikon...

Primary endothelial cells from transgenic mouse embedded in 3D collagen gels of ~ 100 Pa Young's modulus are exposed to 10 micromolar blebbistatin (myosin II ATPase inhibitor). Phase contrast time lap...

Details of the Golgi apparatus seen in 40 nm epon sections of Ptk tissue culture cells after plunge freezing,and freeze substitution. Image recorded at 28,500x with a Philips CM10 TEM operated at 80KV

Human foreskin fibroblasts (HFF1) cells transfected with mKusabira-Orange EB3, a marker for growing microtubule ends. Note the dramatic movement of the bright fluorescent markers toward the cell peri...

Mouse Embryonic Fibroblasts (MEFs) grown on glass coverslips coated with 10 ug/ml Fibronectin. After 24 hrs cells were fixed in 3% paraformaldehyde and stained with mouse antibody to Paxillin, rabbit...

Primary endothelial cells from transgenic mouse expressing myosin heavy chain 2A fused to mCherry (red), transfected with GFP-myosin (green) regulatory light chain expression vector and demonstrate th...

Image shows (actin polymerization at) free barbed ends and F-actin in the lamellipodium of a migrating primary murine embryonic fibroblast. Cell has been mildly permeabilized using saponin during a 2...

Human umbilical vein endothelial cells (HUVECS) labeled for focal adhesions (green) and F-actin (red). HUVECs were plated on polyacrilamide gels (1.5 Kpa) coated with 1.0 mg/ml fibronectin. After 2...

Primary aortic endothelial cells from transgenic mouse embedded in 3D collagen gels. Cell was fixed with 3% paraformaldehyde and stained with mouse antibody to phosphomyosin regulatory light chain (re...